Sustainability Report 2012 Lek d.d.

Sustainability Report 2012 – Lek d.d. Company Profile 4 Table 2: Major environmental and social impacts 4 Indicator Unit 31. 12. 2012 31. 12. 2011 Index 2012/2011 Objectives by 2015 Status 2012 * The figures differ from those published in the Sustainability Report 2011, due to adjustments made to the data on production output and use of raw materials previously stated under the Notes of Table 1. These result in changes in the calculation of efficiency in all the areas. ** The definition of LTIR and TRCR indicators as well as the formula for their calculation are indicated under Item 3.3.2 Monitoring work-related accidents. * Since 2011, in accordance with the Novartis' reporting methodology, waste includes only the waste leaving the site, and not that treated on site. Due to the fact that in 2012 mycelium waste generated by the Lendava fermentation production process was redirected from the site's incinerator to a contractor biogas plant for treatment, the total mycelium waste volume is now reported as waste treated within the site. 1.1.2 Health, safety and environment (HSE) objectives and their realization In the field of HSE, we pursue long-term global objectives set for the period up to 2015, while implementing annual short-term goals. The progress is monitored annualy for indi- vidual sites and for the company as a whole. Data for repor- ting requirements is collected and confirmed in the Novartis DMS (Data Management System) system. Our environmental performance is being improved through: • Regular assessment of the HSE system performance, • Open communication with internal and external publics, and • Every employee's participation in our environmental management efforts. Production processes for pharmaceuticals and active pharmaceutical ingredients differ greatly from site to site, and so do their impacts, particularly environmental ones (waste, emissions into the air, and other). To ensure better transparency of our efforts to manage the relevant envi- ronmental impacts, in this year's report we present our annual objectives by site, thereby enabling us to track the realization of long-term objectives at the level of Lek over the period up to 2015 calculated according to the role of each site. Objectives are set and implemented on the basis of the Lek HSE Policy which is amended, if necessary, at every revision of the Health, Safety and Environment Rules. Efficiency of energy resource use GJ/t 193 222* 87 Water use efficiency m 3 /t 151 165* 92 Waste volumes – efficiency t of waste/t product 3.23 1.57* 206 VOC emissions - efficiency t of VOC/t of product 0.024 0.041* 59 LTIR** - work-related injuries 0.05 0.05 100 and illnesses involving days away from work TRCR** - work-related injuries 0.35 0.39 90 and illnesses requiring more than basic first aid Improving water use efficiency by 10% over 2010. Realized . Water use efficiency improved by 32%. Year 2010: 786 m 3 /t Year 2012: 534 m 3 /t Improving energy efficiency by 10% over 2010. Realized. Energy efficiency improved by almost 24%. Year 2010: 254 GJ/t Year 2012: 193 GJ/t Reducing VOC emissions into the air (h-VOC and nh-VOC) Realized. Emissions reduced by 45%. by 20% over the 2010 figures. Year 2010: 258 t Year 2012: 143 t Reducing waste volumes by 10% over 2010. Partly realized.* Year 2010: 11,000 t Year 2012: 19,000 t Reducing LTIR to 0.1. Realized. 0.05 4 Disclosure GRI 1.2