Sustainability Report 2012 Lek d.d.

Sustainability Report 2012 – Lek d.d. Environment 26 Changing the blister dimension for omeprazole active ingredient Previous blister dimension: 56 x 146 mm 2 Shaping and covering foil consumption compared (FP manufacture in 2012) New blister dimension: 50 x 140 mm 2 Reduction: • Blister surface – 17% • Shaping foil weight – 20% • Covering foil weight – 15% 0 10,000 20,000 30,000 Shaping foil Covering foil 40,000 50,000 60,000 – 20% – 15% 70,000 } } Weight (kg) 56 x 146 50 x 140 2.2.5 Water consumption and energy efficiency In 2012, the efficiency of water, electricity and natural gas use per unit of product was improved once again, which was the result of many years of systematic endeavors in this area. At the level of Lek, the energency efficiency per tonne of product improved by 13%. We have often mentioned fluctuations resulting from the changes in production volume and structure which are also the major cause of absolute and relative variations in the energy and water consumption at individual sites. As the production outputs of a single product or a small number of products at the Lendava and Prevalje sites are relative- ly stable, a year-on-year comparison of water and energy use efficiency provides a true picture of trends recorded at these two sites. Major variations in the specific use of water and energy resources recorded at the Ljubljana and Men- ge‰ sites are due to the versatility of the sites’ portfolios. The manufacture of individual products at the mentioned sites is subject to major market fluctuations. * Due to the improved method for acquiring data on the realization of various finished pharmaceutical products manufacture and on the mass flows of raw materials at the Ljubljana site, there was a change in the data for previous years. 2008 GJ/t 2,573 97 476 80 213 2009 GJ/t 2,450 174 631 73 315 2010 GJ/t 2,240 115 720 66 254 2011 GJ/t 2,004 106 677 53 222 2012 GJ/t 1,697 92 613 56 193 Year Unit Lendava Ljubljana* Prevalje Menge‰ Lek (Total)* Table 4: Efficiency of energy resource use per unit of product 27 27 EMAS Core Indicator

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